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decision support for vaccine efficacy trial design during an emerging outbreak

How does it work?

  1. Explore decisions and their implications using the decision tree tool.
  2. Take notes.
  3. Generate, publish, and share reports.
  4. Or, explore one of the Zika scenario below.

The design and execution of rigorous, fast, and ethical vaccine efficacy trials can be challenging during epidemics of emerging diseases. Response to an urgent public health crisis requires accelerated research even as emerging epidemics themselves evolve rapidly and inherently are less well understood. The InterVax Tool is an online visual, interactive tool developed to help diverse stakeholders navigate the various epidemiological, logistical and ethical decisions involved in the design of a vaccine efficacy trial during emerging epidemics.

The tool is not intended to provide a black box decision tree for identifying an optimal trial design, but rather a means of facilitating a transparent, collaborative and comprehensive discussion of the relevant decisions and for recording the decision process.

Users can get started with the Video Tutorial (linked above) and can also explore pre-annotated scenarios on the 2014-2016 West African Ebola Epidemic and the 2016 Zika Epidemic in the Americas (linked at bottom).

Statement on use of personal details

Your email address is stored in a database and processed only to save and retrieve decision trees in the InterVax-Tool. We do not share entered details (email addresses, content of trees, any other user information) with any other organizations. We do not add any email addresses to any mailing lists. We will hold the email addresses for the lifetime of the InterVax-Tool site.

If you would like your personal information removed from the database, email

Enter a title to create a new tree
Enter a title to create a new tree
Or choose from an existing tree to view/edit
    Decision tree questions:
            Key Considerations (related to selected decision above)